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Binge on the latest quizzes delivered right to your inbox. Come on in and hunker down for the long haul. Do You Know the Benefits of Walking? Have at-Home Tests for the Flu? This article is from the WebMD News Archive This content has not been reviewed within the past year and may not represent WebMD’s most up-to-date information.

March 15, 2005 — Vitamin E harms more than it helps, a large study shows. Vitamin E is a powerful antioxidant, thought to clear the body of harmful oxygen compounds called free radicals. Lonn led a seven-year-long, international study that enrolled thousands of people at high risk of heart disease. The findings added to suspicions raised by prior studies: Vitamin E isn’t worth it. We saw definitely no benefit, and at least the potential for harm,” Lonn tells WebMD. Lott and colleagues report their findings in the March 16 issue of The Journal of the American Medical Association.

After four years, those who took vitamin E had no fewer heart attacks, strokes, cancers, or cancer deaths. But many experts wondered whether that was long enough for vitamin E to help. So Lonn and colleagues extended the study for another three years. Unexpectedly, they did see one difference.

Patients taking vitamin E had significantly more heart failure. But since the vitamin did no good at all, it’s a risk not worth taking. If there is no benefit from taking something, you shouldn’t take even a small risk of harm,” Lonn says. There is no need to worry if you take a multivitamin that contains recommended amounts of vitamin E. Vitamin E has been very clearly shown to be of no benefit to the general problem of cancer or heart disease,” Brown says. Studies are still looking at whether vitamin E can help prostate cancer, cancer, and severe macular degeneration. Brown’s editorial accompanies the Lott study in the March 16 issue of JAMA.